At one time it was thought that LLLT was ineffective when used with cortisone. Newer studies are showing that LLLT actually may have a synergistic effect with cortisone. This animal study aimed to assess the effect of LLLT associated with and without dexamethasone on inflammation and wound healing in surgical wounds.

The results showed that LLLT and dexamethasone acted in a similar pattern to reduce acute inflammation! Collagen synthesis and tissue healing were more intense in the laser group and LLLT was effective in reducing swelling and accelerated repair, even in the presence of dexamethasone.
(Photomed Laser Surg. 2010 Oct;28(5):639-46)